Working with Molecular Genetics

by Ross C. Hardison, 2005

Professor of Biochemistry, The Pennsylvania State University, University Park, PA 16802

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This online textbook covers major topics in molecular genetics in a problems-based approach. It grew out of teaching a course for upper level undergraduates and graduate students at the Pennsylvania State University (BMB400).

The copyright is held by the author, Ross C. Hardison. Anyone is free to read and use this information for any purpose EXCEPT for profit. I make it freely available, so keep it free. For instance, if you are teaching a class and want to point students to it, please do so. If you want to use this material to learn some molecular genetics, please do so. If you want to use some of the figures in a report, do so, just list this page as your source. If you want to take any or all of this material and publish it as a book for your profit - DON'T!

The material was current as of fall, 2002. Most of the material is relatively "stable", so hopefully it will be useful for some time to come. I do not intend to update it very often, if at all. However, feedback is always welcome, and may inspire me to edit this some more.

Various guest lecturers have added important material to this course and book. In particular I thank Tracy Nixon (Dept. BMB, PSU) for his contributions to Chapter 16 and Jerry Workman (formerly in BMB at PSU, now at the Stowers Institute) for his contributions to Chapter 20. Some of the images are derived from other books, articles and websites. I have tried to cite all those sources; please forgive me if I have overlooked any.

You can access both html and pdf versions of the chapters. The pdfs are more accurate representations, but html is provided for convenience. The original material was generated in Microsoft Word, and the html is generated by the "Word to html" conversion facility within Word. I know that some things (like arrows, exponents, and even positions of figures with respect to text) are not rendered accurately, so beware of this problem. Some of the images were made years ago in MacDraw (pict files), and are not rendered all that well. A small number are hand-drawn and scanned in; these are hard to read. However, most of the figures should be legible, especially in the pdfs.

Ross Hardison, January 12, 2005

Page created: Wednesday, 12-Jan-2005; last update 30-November-2015