Interests
- Genome evolution
- Molecular mechanisms of carcinogenesis
Education
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Ph.D. in OncologyUniversity of Wisconsin-Madison
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B.S. in MicrobiologyPenn State University
Publications
(2025).
Replicative DNA polymerase Epsilon and Delta holoenzymes show wide ranging inhibition at G-Quadruplexes in the human genome.
NUCLEIC ACIDS RES.
(2023).
Accurate sequencing of DNA motifs able to form alternative (non-B) structures.
GENOME RES.
(2022).
Variation in G-quadruplex Sequence and Topology Differentially Impacts Human DNA Polymerase Fidelity.
DNA REPAIR.
(2021).
Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome.
GENOME RES.
(2021).
Non-B DNA: A major contributor to small- and large-scale variation in nucleotide substitution frequencies across the genome.
NUCLEIC ACIDS RES.
(2018).
Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate.
GENOME RES.
(2016).
Reverse Transcription Errors and RNA–DNA Differences at Short Tandem Repeats.
MOL BIOL EVOL.
(2015).
Accurate typing of short tandem repeats from genome-wide sequencing data and its applications.
GENOME RES.
(2014).
Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes.
PLOS GENET.
(2013).
Mature Microsatellites: Mechanisms Underlying Dinucleotide Microsatellite Mutational Biases in Human Cells.
G3-GENES GENOM GENET.
(2013).
Distinct Mutational Behaviors Differentiate Short Tandem Repeats from Microsatellites in the Human Genome.
GENOME BIOL EVOL.
(2012).
A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?.
GENOME RES.