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In vivo detection of DNA secondary structures using Permanganate/S1 Footprinting with Direct Adapter Ligation and Sequencing (PDAL-Seq)

DNA secondary structures are essential elements of the genomic landscape, playing a critical role in regulating various cellular processes. These structures refer to …

a-lahnsteiner

Using Statistics to Shed Light on the Dynamics of the Human Genome: A Review

In this article we review a number of recent studies in which information derived from genomic alignments and data concerning composition, location and biochemical features of the …

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Francesca Chiaromonte

Rapid Evolution of Genes on the Human X Chromosome

AbstractThere is considerable interest in determining the sequences that are evolving rapidly in our genome, as these may well confer an advantage that has helped to propel the …

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Erika Kvikstad

Mitochondrial Genome: Clues about the Evolution of Extant Equids and Genomic Diversity of Horse Breeds

Summary This chapter contains sections titled: Introduction Evolution of the Family Equidae Przewalski's Horse and Horse Domestication History of Horse Breeds Adaptation in Horse …

cc-steiner

Molecular Clocks

Abstract The molecular clock hypothesis postulates that the rate of evolution in a macromolecule is approximately constant per year over time and among different evolutionary …

w-h-li

Domain Duplication and Gene Elongation

Abstract A protein domain is a well-defined region within a protein that performs a specific function. Thus duplication of a protein domain may enhance the function of the protein. …

w-h-li