Domain Duplication and Gene Elongation

Jul 15, 2006· W-H Li, KD Makova · 0 min read
Abstract
Abstract A protein domain is a well-defined region within a protein that performs a specific function. Thus duplication of a protein domain may enhance the function of the protein. The fact that many extant proteins contain duplicated domains suggests that present-day complex proteins have evolved from simple proteins mainly via domain duplication.
Type
Publication
Encyclopedia of Life Sciences
publication
Kateryna Makova, Ph.D.
Authors
Kateryna Makova, Ph.D.
Professor
Kateryna is interested in genomics, evolution, and human genetics. Her lab studies mutations using both computational and experimental approaches. Additional topics of interest include sex chromosome evolution and genomics of childhood obesity.