Childhood obesity

Obesity is becoming the major epidemic of the 21st century, and we are studying this disease in an integrated way - from the perspective of genomics, microbiomics, and epigenomics. We are following a large group of newborn children until they are at least 3 years of age, and will be finding genes linked to the development of obesity in some of them. This collaboration includes clinicians, statisticians, and social scientists to obtain a multifaceted picture of this important phenotype. Collaborators: Ian Paul, Francesca Chiaromonte.


Press Releases

UNIVERSITY PARK, PA. — Newly developed risk scores synthesize genetic information into an easy-to-interpret metric that could help …

Millions of tiny dots litter the canvas, each independently just a splotch of unmixed pigment but together a masterpiece of illusion …

The composition of oral microbiota – the collection of microorganisms, including beneficial bacteria, residing in the mouth …


. Methylation profiles at birth linked to early childhood obesity. J DEV ORIG HEALTH DIS, 2024.

Childhood Obesity Paper Link

. Constructing a polygenic risk score for childhood obesity using functional data analysis. ECONOM STAT, 2023.

Childhood Obesity Paper Link

. INSIGHT responsive parenting educational intervention for firstborns is associated with growth of secondborn siblings. OBESITY, 2022.

Childhood Obesity Paper Link

. Metabolomic profiling of stool of two-year old children from the INSIGHT study reveals links between butyrate and child weight outcomes. PED OBESITY, 2022.

Childhood Obesity Paper Link

. Associations between stool micro-transcriptome, gut microbiota, and infant growth. J DEV ORIG HLTH DIS, 2021.

Childhood Obesity Paper Link

. Polygenic risk score based on weight gain trajectories is a strong predictor of childhood obesity. BIORXIV, 2019.

Childhood Obesity Paper Link

. Child Weight Gain Trajectories Linked To Oral Microbiota Composition. SCI REP-UK, 2018.

Childhood Obesity Paper Link Press Release

. The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) study. BMC PEDIATR, 2014.

Childhood Obesity Paper Link