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Beyond the double helix: Alternative DNA conformations in ape genomes
UNIVERSITY PARK, Pa. — Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA …
Sam Sholtis
Apr 24, 2025
Complete genome sequences of six ape species unveiled
Credit: guenterguni/Getty Images. All Rights Reserved. UNIVERSITY PARK, Pa. — Differences among the DNA of seven ape species — …
Christine Yu
Apr 9, 2025
Complete X and Y chromosome sequences of living great ape species determined
Newly generated, complete “end-to-end” reference genomes for the sex chromosomes of five great ape species and one lesser ape species — …
Penn State Eberly College of Science
May 29, 2024
DNA sequence of the human Y chromosome fully determined for first time
Listen to the Science Friday podcast where Adam Phillippy and Kateryna Makova discuss the challenges of sequencing the Y chromosome, …
Francisco Tutella
Aug 23, 2023
Are egg cells in aging primates protected from mutations?
New mutations occur at increasing rates in the mitochondrial genomes of developing egg cells in aging rhesus monkeys, but the increases …
Sam Sholtis
Apr 4, 2022
New approach can help identify young children most at risk for obesity
UNIVERSITY PARK, PA. — Newly developed risk scores synthesize genetic information into an easy-to-interpret metric that could help …
Gail McCormick
Jan 10, 2022
A new class of functional elements in the human genome?
Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called G-quadruplexes (G4s) show …
Sam Sholtis
Jun 29, 2021
Unusual DNA folding increases the rates of mutations
DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in …
Sam Sholtis
Feb 8, 2021
Evolution of the Y chromosome in great apes deciphered
Researchers have reconstructed the ancestral sequence of the great ape Y chromosome by comparing three existing (gorilla, human, and …
Sam Sholtis
Oct 6, 2020
Scientists take a step toward understanding 'jumping genes' effect on the genome
Comparisons of DNase Hypersensitive Site (DHS) signals among L1 flanking regions and control.The figure illustrates the distribution of …
Matt Swayne
Sep 29, 2020
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