Penn State University Center for Comparative Genomics and Bioinformatics
Miller Lab, LASTZ
Introduction
LASTZ is a program for aligning DNA sequences, a pairwise aligner. Originally
designed to handle sequences the size of human chromosomes and from different
species, it is also useful for sequences produced by NGS sequencing
technologies such as Roche 454.
Citing LASTZ
Harris, R.S. (2007) Improved pairwise alignment of genomic DNA. Ph.D. Thesis, The
Pennsylvania State University.
That Ph.D. thesis is here.
Links
Source code for latest official release
(gzipped tar file of source code; 1.04.15, 2021-Aug-26)
LASTZ documentation
(
what’s new in lastz-1.04.15)
LASTZ repository on github, which mirrors the release tarball.
Documentation for the LAV alignment format
(default output from LASTZ)
Bob Harris’s Ph.D. Thesis, describing LASTZ.
Older releases, including the long time "official" release 1.02.00
Other releases, between Jan/2010 and Aug/2021
(Some not officially released)
Related tools
(As is, with little or no documentation)
Miller Lab main page
Contact
Bob Harris: 