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Xinru Zhang

Ph.D. student

Interests

  • Molecular evolution

Education

  • B.S. in Biology,

    Wuhan University, China

Biography

Xinru is a Ph.D. student in the Bioinformatics and Genomics Program co-advised by Dr. Kateryna Makova and Dr. Yi-Fei Huang. Currently, she is studying the evolution of human genome, specifically G-quadruplexes and regulatory elements. By integrating machine learning and phylogenetic inferences, she aims to explore the connection between evolutionary biology and human health.

Publications

KD Makova, BD Pickett, RS Harris, GA Hartley, M Cechova, K Pal, S Nurk, D Yoo, Q Li, P Hebbar, BC McGrath, F Antonacci, M Aubel, A Biddanda, M Borchers, E Bomberg, GG Bouffard, SY Brooks, L Carbone, L Carrel, A Carroll, PC Chang, CS Chin, DE Cook, SJC Craig, L de Gennaro, M Diekhans, A Dutra, GH Garcia, PGS Grady, RE Green, D Haddad, P Hallast, WT Harvey, G Hickey, DA Hillis, SJ Hoyt, H Jeong, K Kamali, SL Kosakovsky Pond, TM LaPolice, C Lee, AP Lewis, YE Loh, P Masterson, RC McCoy, P Medvedev, KH Miga, KM Munson, E Pak, B Paten, BJ Pinto, T Potapova, A Rhie, JL Rocha, F Ryabov, OA Ryder, S Sacco, K Shafin, VA Shepelev, V Slon, SJ Solar, JM Storer, PH Sudmant, Sweetalana, A Sweeten, MG Tassia, F Thibaud-Nissen, M Ventura, MA Wilson, AC Young, H Zeng, X Zhang, ZA Szpiech, CD Huber, JL Gerton, SV Yi, MC Schatz, IA Alexandrov, S Koren, RJ O’Neill, E Eichler, AM Phillippy. The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes. NATURE, 2024.

Sex chromosome Video Paper Link Press release

X Zhang, B Fang, YF Huang. Transcription factor binding sites are frequently under accelerated evolution in primates. NAT COMMUN, 2023.

Regional variation Paper Link

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