Hardison Lab Datasets and Supplements

e-mail address: rch8@psu.edu
Current Directory Entry

My laboratory is generating various datasets useful in comparative genomics and in erythroid gene regulation. Although every effort is made to deposit these in appropriate databases, sometimes it is most convenient just to provide the data files here.

If you use these datasets, please cite the listed reference in any publications.

Mapping DNA segments occupied by GATA1 and the response in gene expression throughout the the mouse erythroid genome; Distinguishing induction from repression

Identification of DNA segments occupied by GATA1 on mouse chromosome 7, and demonstration that binding site motifs in enhancers are subject to evolutionary constraint

Predictions of erythroid cis-regulatory modules and results of experimental tests

Predictions of cis-regulatory modules genome-wide

Reference sets of known CRMs in the human beta-globin gene complex

Microarray expression results on MEL_RL5 cells induced to mature to hemoglobinized erythroblasts with HMBA.

Conservation and constraint in ENCODE predicted transcriptional regulatory regions

Co-variation in frequencies of substitution, deletion, transposition and recombination during eutherian evolutions

Presentations on using vertebrate genome comparisons to predict and test cis-regulatory modules

Page created: Thursday, 13-Jan-2005, updated 07-Oct-2009