Details for gene set GOBP_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR

Table: GSEA Results Summary

Dataset	de_results_collapsed
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	GOBP_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL
Enrichment Score (ES)	0.27804247
Normalized Enrichment Score (NES)	2.5360198
Nominal p-value	0.0
FDR q-value	0.0015863322
FWER p-Value	0.031

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	H2BC12	H2B clustered histone 12 [Source:HGNC Symbol;Acc:HGNC:13954]	33	7.423	-0.0013	Yes
2	ADRB2	adrenoceptor beta 2 [Source:HGNC Symbol;Acc:HGNC:286]	53	6.961	0.0039	Yes
3	TRIM21	tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312]	69	6.644	0.0105	Yes
4	EGR2	early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239]	84	6.405	0.0172	Yes
5	WSB2	WD repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:19222]	121	5.760	0.0106	Yes
6	ASB1	ankyrin repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:16011]	164	5.333	-0.0002	Yes
7	H2BC14	H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750]	174	5.208	0.0065	Yes
8	RFFL	ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821]	189	5.103	0.0103	Yes
9	H2BC7	H2B clustered histone 7 [Source:HGNC Symbol;Acc:HGNC:4752]	193	5.068	0.0199	Yes
10	KLHL12	kelch like family member 12 [Source:HGNC Symbol;Acc:HGNC:19360]	233	4.852	0.0097	Yes
11	GAN	gigaxonin [Source:HGNC Symbol;Acc:HGNC:4137]	255	4.750	0.0089	Yes
12	JADE2	jade family PHD finger 2 [Source:HGNC Symbol;Acc:HGNC:22984]	263	4.694	0.0155	Yes
13	SPRY2	sprouty RTK signaling antagonist 2 [Source:HGNC Symbol;Acc:HGNC:11270]	265	4.684	0.0254	Yes
14	TRIM32	tripartite motif containing 32 [Source:HGNC Symbol;Acc:HGNC:16380]	270	4.646	0.0335	Yes
15	ANAPC10	anaphase promoting complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:24077]	273	4.630	0.0427	Yes
16	H2BC5	H2B clustered histone 5 [Source:HGNC Symbol;Acc:HGNC:4747]	279	4.611	0.0502	Yes
17	IFI27	interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397]	281	4.600	0.0599	Yes
18	OTUD7B	OTU deubiquitinase 7B [Source:HGNC Symbol;Acc:HGNC:16683]	329	4.433	0.0444	Yes
19	PTPN22	protein tyrosine phosphatase non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652]	334	4.419	0.0520	Yes
20	DCUN1D5	defective in cullin neddylation 1 domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28409]	341	4.371	0.0585	Yes
21	USP28	ubiquitin specific peptidase 28 [Source:HGNC Symbol;Acc:HGNC:12625]	343	4.361	0.0676	Yes
22	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:30628]	351	4.332	0.0734	Yes
23	KCTD11	potassium channel tetramerization domain containing 11 [Source:HGNC Symbol;Acc:HGNC:21302]	355	4.328	0.0814	Yes
24	VCPIP1	valosin containing protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30897]	362	4.312	0.0877	Yes
25	OBI1	ORC ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:20308]	367	4.284	0.0951	Yes
26	G2E3	G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338]	387	4.197	0.0941	Yes
27	STAMBPL1	STAM binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:24105]	389	4.188	0.1029	Yes
28	TRIM58	tripartite motif containing 58 [Source:HGNC Symbol;Acc:HGNC:24150]	391	4.186	0.1116	Yes
29	NUP37	nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929]	399	4.164	0.1171	Yes
30	H2BC15	H2B clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:4749]	408	4.126	0.1219	Yes
31	FANCL	FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748]	429	4.050	0.1201	Yes
32	HERC5	HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368]	468	3.952	0.1084	Yes
33	DDB2	damage specific DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2718]	476	3.934	0.1134	Yes
34	STAM2	signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358]	486	3.909	0.1172	Yes
35	RNF34	ring finger protein 34 [Source:HGNC Symbol;Acc:HGNC:17297]	487	3.906	0.1258	Yes
36	DAXX	death domain associated protein [Source:HGNC Symbol;Acc:HGNC:2681]	496	3.895	0.1302	Yes
37	AXIN1	axin 1 [Source:HGNC Symbol;Acc:HGNC:903]	509	3.850	0.1322	Yes
38	H2BC6	H2B clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4753]	517	3.832	0.1370	Yes
39	RNF121	ring finger protein 121 [Source:HGNC Symbol;Acc:HGNC:21070]	529	3.805	0.1395	Yes
40	DESI2	desumoylating isopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:24264]	543	3.766	0.1408	Yes
41	UBE2E3	ubiquitin conjugating enzyme E2 E3 [Source:HGNC Symbol;Acc:HGNC:12479]	546	3.759	0.1481	Yes
42	FBXO5	F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584]	561	3.735	0.1488	Yes
43	H2BC13	H2B clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4748]	563	3.725	0.1565	Yes
44	RRAGA	Ras related GTP binding A [Source:HGNC Symbol;Acc:HGNC:16963]	569	3.718	0.1621	Yes
45	H2BC11	H2B clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4761]	582	3.688	0.1638	Yes
46	RNF25	ring finger protein 25 [Source:HGNC Symbol;Acc:HGNC:14662]	592	3.666	0.1671	Yes
47	BMI1	"BMI1 proto-oncogene, polycomb ring finger [Source:HGNC Symbol;Acc:HGNC:1066]"	594	3.657	0.1746	Yes
48	FBXO32	F-box protein 32 [Source:HGNC Symbol;Acc:HGNC:16731]	597	3.655	0.1816	Yes
49	SHPRH	SNF2 histone linker PHD RING helicase [Source:HGNC Symbol;Acc:HGNC:19336]	603	3.648	0.1870	Yes
50	RFWD3	ring finger and WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:25539]	615	3.627	0.1891	Yes
51	APC	APC regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:583]	617	3.622	0.1966	Yes
52	FYN	"FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037]"	621	3.619	0.2030	Yes
53	PSMF1	proteasome inhibitor subunit 1 [Source:HGNC Symbol;Acc:HGNC:9571]	647	3.564	0.1975	Yes
54	SENP1	SUMO specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:17927]	651	3.560	0.2037	Yes
55	TRIM52	tripartite motif containing 52 [Source:HGNC Symbol;Acc:HGNC:19024]	671	3.536	0.2013	Yes
56	PSMD14	"proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889]"	678	3.522	0.2059	Yes
57	PCGF1	polycomb group ring finger 1 [Source:HGNC Symbol;Acc:HGNC:17615]	688	3.504	0.2088	Yes
58	CNOT4	CCR4-NOT transcription complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:7880]	692	3.497	0.2150	Yes
59	TRIM59	tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834]	714	3.467	0.2114	Yes
60	UBOX5	U-box domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17777]	717	3.458	0.2179	Yes
61	NUP160	nucleoporin 160 [Source:HGNC Symbol;Acc:HGNC:18017]	718	3.456	0.2256	Yes
62	RIPK1	receptor interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:10019]	724	3.438	0.2305	Yes
63	H2BC4	H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757]	730	3.433	0.2354	Yes
64	TULP4	TUB like protein 4 [Source:HGNC Symbol;Acc:HGNC:15530]	736	3.428	0.2403	Yes
65	DCAF13	DDB1 and CUL4 associated factor 13 [Source:HGNC Symbol;Acc:HGNC:24535]	738	3.427	0.2474	Yes
66	HLTF	helicase like transcription factor [Source:HGNC Symbol;Acc:HGNC:11099]	747	3.399	0.2506	Yes
67	CDC14B	cell division cycle 14B [Source:HGNC Symbol;Acc:HGNC:1719]	757	3.387	0.2533	Yes
68	CBLB	Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542]	763	3.380	0.2581	Yes
69	TRIM26	tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962]	792	3.323	0.2504	Yes
70	RNF26	ring finger protein 26 [Source:HGNC Symbol;Acc:HGNC:14646]	795	3.320	0.2566	Yes
71	RYBP	RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480]	803	3.309	0.2602	Yes
72	TRIM37	tripartite motif containing 37 [Source:HGNC Symbol;Acc:HGNC:7523]	806	3.307	0.2664	Yes
73	PIAS3	protein inhibitor of activated STAT 3 [Source:HGNC Symbol;Acc:HGNC:16861]	811	3.295	0.2716	Yes
74	USP11	ubiquitin specific peptidase 11 [Source:HGNC Symbol;Acc:HGNC:12609]	824	3.279	0.2724	Yes
75	RANGAP1	Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854]	828	-3.278	0.2780	Yes
76	CTNNB1	catenin beta 1 [Source:HGNC Symbol;Acc:HGNC:2514]	848	-3.304	0.2751	No
77	LRRK2	leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618]	866	-3.326	0.2734	No
78	MINDY1	MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648]	899	-3.378	0.2637	No
79	RPL23	ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316]	974	-3.487	0.2316	No
80	KAT2A	lysine acetyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:4201]	1001	-3.539	0.2255	No
81	PELI2	pellino E3 ubiquitin protein ligase family member 2 [Source:HGNC Symbol;Acc:HGNC:8828]	1042	-3.605	0.2120	No
82	ZMIZ1	zinc finger MIZ-type containing 1 [Source:HGNC Symbol;Acc:HGNC:16493]	1083	-3.666	0.1986	No
83	BCL2	BCL2 apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:990]	1123	-3.723	0.1859	No
84	CDK5RAP3	CDK5 regulatory subunit associated protein 3 [Source:HGNC Symbol;Acc:HGNC:18673]	1145	-3.762	0.1829	No
85	NDFIP1	Nedd4 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:17592]	1176	-3.812	0.1752	No
86	TSPO	translocator protein [Source:HGNC Symbol;Acc:HGNC:1158]	1244	-3.951	0.1480	No
87	RNF144B	ring finger protein 144B [Source:HGNC Symbol;Acc:HGNC:21578]	1257	-3.988	0.1503	No
88	SIAH1	siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857]	1265	-4.010	0.1555	No
89	USP35	ubiquitin specific peptidase 35 [Source:HGNC Symbol;Acc:HGNC:20061]	1280	-4.036	0.1569	No
90	LAPTM5	lysosomal protein transmembrane 5 [Source:HGNC Symbol;Acc:HGNC:29612]	1282	-4.039	0.1653	No
91	HIF1A	hypoxia inducible factor 1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:4910]	1307	-4.100	0.1615	No
92	SUMO1P1	SUMO1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33148]	1328	-4.138	0.1599	No
93	NLRP3	NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400]	1336	-4.158	0.1653	No
94	SASH1	SAM and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19182]	1368	-4.249	0.1581	No
95	LMO7	LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:6646]	1373	-4.256	0.1653	No
96	ARRB2	arrestin beta 2 [Source:HGNC Symbol;Acc:HGNC:712]	1376	-4.263	0.1737	No
97	MEFV	"MEFV innate immuity regulator, pyrin [Source:HGNC Symbol;Acc:HGNC:6998]"	1411	-4.347	0.1650	No
98	MID2	midline 2 [Source:HGNC Symbol;Acc:HGNC:7096]	1432	-4.386	0.1640	No
99	SOX4	SRY-box transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11200]	1433	-4.389	0.1737	No
100	UBE2E2	ubiquitin conjugating enzyme E2 E2 [Source:HGNC Symbol;Acc:HGNC:12478]	1485	-4.515	0.1563	No
101	SOCS3	suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391]	1631	-4.976	0.0894	No
102	RNF217	ring finger protein 217 [Source:HGNC Symbol;Acc:HGNC:21487]	1639	-4.994	0.0967	No
103	RNF130	ring finger protein 130 [Source:HGNC Symbol;Acc:HGNC:18280]	1697	-5.173	0.0775	No
104	CISH	cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984]	1757	-5.514	0.0580	No
105	ZBTB16	zinc finger and BTB domain containing 16 [Source:HGNC Symbol;Acc:HGNC:12930]	1803	-5.788	0.0466	No
106	RNF165	ring finger protein 165 [Source:HGNC Symbol;Acc:HGNC:31696]	1825	-5.983	0.0486	No
107	TBC1D7	TBC1 domain family member 7 [Source:HGNC Symbol;Acc:HGNC:21066]	1827	-5.992	0.0613	No
108	NEDD4L	NEDD4 like E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7728]	1861	-6.278	0.0575	No