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Di (Bruce) Chen

Ph.D. student

Interests

Education

Biography

Born and raised up in Nanjing, China. Trained as a computational biologist and amateur violinist. Big fan of backpacking, sci-fi, and research. Current work leverages bioinformatics tools and statistics in comparative genomics, with special interest in the regional variation of mutation rate in human genome.

Publications

WM Guiblet, MA Cremona, RS Harris, D Chen, KA Eckert, F Chiaromonte, Y Huang, KD Makova. Non-B DNA: A major contributor to small- and large-scale variation in nucleotide substitution frequencies across the genome. NUCLEIC ACIDS RES, 2021.

Regional variation Non-B DNA & Microsatellite Paper Link

M Cechova, R Vegesna, M Tomaszkiewicz, RS Harris, D Chen, S Rangavittal, P Medvedev, KD Makova. Dynamic evolution of great ape Y chromosomes. P NATL ACAD SCI USA, 2020.

Sex chromosome Paper Link

D Chen, MA Cremona, Z Qi, RD Mitra, F Chiaromonte, KD Makova. Human L1 Transposition Dynamics Unraveled with Functional Data Analysis. MOL BIOL EVOL, 2020.

Regional variation Paper Link

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