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Mitchell M. Holland

Associate Professor of Biochemistry and Molecular Biology, Pennsylvania State University

Personal website

Interests

  • Forensic biology
  • Forensic mitochondrial (mt) DNA analysis

Education

  • Ph.D. in Biochemistry, 1989

    The University of Maryland

  • B.S. in Chemistry, 1984

    Hobart College

Biography

Dr. Holland is a Fellow in the American Academy of Forensic Sciences, and has served as an associate professorial lecturer and adjunct faculty member at various colleges and universities. Dr. Holland has been on the Editorial Board of the Journal of Forensic Sciences and a member of the Advisory Board of the International Journal of Legal Medicine. He has held positions on governmental and company advisory boards and has been recognized by the FBI and others for his work. Dr. Holland has had extensive experience with human remains identification cases, including the identification of victims from the World Trade Center disasters and from numerous commercial airline accidents. His rearch group is focused on advancing forensic DNA applications, especially in the area of forensic mitochondrial (mt) DNA analysis.

Publications

MM Holland, KD Makova, JA McElhoe. Deep-Coverage MPS Analysis of Heteroplasmic Variants within the mtGenome Allows for Frequent Differentiation of Maternal Relatives. GENES-BASEL, 2018.

Mitochondrial Paper Link

JA McElhoe, MM Holland, KD Makova, MS-W Su, IM Paul, CH Baker, SA Faith, B Young. Development and assessment of an optimized next-generation DNA sequencing approach for the mtgenome using the Illumina MiSeq. FORENSIC SCI INT-GEN, 2014.

Mitochondrial Paper Link

B Rebolledo-Jaramillo, MS-W Su, N Stoler, JA McElhoe, B Dickins, D Blankenberg, TS Korneliussen, F Chiaromonte, R Nielsen, MM Holland, IM Paul, A Nekrutenko, KD Makova. Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA. P NATL ACAD SCI USA, 2014.

Mitochondrial Paper Link

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